Buy Lidocaine Online
Lidocaine is a local anesthetic. It works by stopping nerves from sending pain signals. Lidocaine comes as a transdermal patch applied directly to the skin for localized relief of acute hypersensitivity and chronic pain in postherpetic neuralgia.
Lidocaine is one of several ACLS drugs used to treat cardiac arrest from ventricular tachycardia (VT) and Ventricular Fibrillation (VF). Lidocaine is considered a second-line antiarrhythmic drug and should be administered in VF/VT cases where amiodarone is either unavailable or ineffective. While lidocaine is a well-known and established ACLS medication, there is actually no proven short-term or long-term effectiveness following cardiac arrest. Therefore, it’s use is not recommended routinely after cardiac arrest, but rather should be considered following ROSC.
How to use Lidocaine
Before use on the skin, clean and dry the affected area as directed. Apply a thin layer of medication to the affected area of skin, usually 2 to 3 times a day or as directed.
If you are using the spray, shake the canister well before using. While holding the canister 3-5 inches (8-13 centimeters) from the affected area, spray until wet. If the affected area is on the face, spray the medication onto your hand and apply to the face. Do not spray near your eyes, nose, or mouth.
If you are using the foam, shake the canister well before using. Spray the foam onto your hand and apply to the affected area.
Do not use on large areas of the body, cover the area with waterproof bandages or plastic, or apply heat unless directed to do so by your doctor. These may increase the risk of serious side effects.
Wash hands immediately after use unless you are treating an area on the hands. Avoid getting the product in eyes, nose, or ears. If the medication gets in these areas, rinse the area immediately with clean water.
Dosage is based on your medical condition and response to therapy. Do not use more of this product, use it more often, or keep using it longer than prescribed by your doctor. If you are using a nonprescription product, follow all the directions on the product package, or use as directed by your doctor. If there is an infection or sore in the area to be treated, do not use this medication without consulting your doctor first.
Before using lidocaine, tell your doctor or pharmacist if you are allergic to it; or to other amide type anesthetics (e.g., bupivacaine, prilocaine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: broken skin/infection in the area where lidocaine is to be used, heart disease, liver disease.
Caution is advised when using this drug in children because they may be more sensitive to the side effects of the drug.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This medication passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Dosage & Administration
When used to treat cardiac arrest from VT/VF, the initial dose should be 1-1.5 mg/kg IV/IO.
For refractory VF, an additional 0.5-0.75 mg/kg IV push may be given, then repeated every 5-10 minutes, with a max of 3 doses or a total of 3 mg/kg.
In stable VT situations, doses spanning between 0.5-0.75 mg/kg up to 1.5 mg/kg may be administered. Repeat 0.5-0.75 mg/kg to a max of 3 mg/kg.
If maintenance infusion is needed, administer dose of 1-4 mg/min.
Recommended Dosages summarizes the recommended volumes and concentrations of lidocaine Injection for various types of anesthetic procedures. The dosages suggested in this table are for normal healthy adults and refer to the use of epinephrine-free solutions. When larger volumes are required, only solutions containing epinephrine should be used except in those cases where vasopressor drugs may be contraindicated.
There have been adverse event reports of chondrolysis in patients receiving intra-articular infusions of local anesthetics following arthroscopic and other surgical procedures. Lidocaine is not approved for this use.
These recommended doses serve only as a guide to the amount of anesthetic required for most routine procedures. The actual volumes and concentrations to be used depend on a number of factors such as type and extent of surgical procedure, depth of anesthesia and degree of muscular relaxation required, duration of anesthesia required, and the physical condition of the patient. In all cases the lowest concentration and smallest dose that will produce the desired result should be given. Dosages should be reduced for children and for the elderly and debilitated patients and patients with cardiac and/or liver disease.
The onset of anesthesia, the duration of anesthesia and the degree of muscular relaxation are proportional to the volume and concentration (ie, total dose) of local anesthetic used. Thus, an increase in volume and concentration of lidocaine Injection will decrease the onset of anesthesia, prolong the duration of anesthesia, provide a greater degree of muscular relaxation and increase the segmental spread of anesthesia. However, increasing the volume and concentration of lidocaine Injection may result in a more profound fall in blood pressure when used in epidural anesthesia. Although the incidence of side effects with lidocaine HCl is quite low, caution should be exercised when employing large volumes and concentrations, since the incidence of side effects is directly proportional to the total dose of local anesthetic agent injected.
For intravenous regional anesthesia, only the 50 mL single dose vial containing lidocaine HCl 0.5% Injection should be used.
- Adverse experiences following the administration of lidocaine HCl are similar in nature to those observed with other amide local anesthetic agents. These adverse experiences are, in general, dose-related and may result from high plasma levels caused by excessive dosage, rapid absorption or inadvertent intravascular injection, or may result from a hypersensitivity, idiosyncrasy or diminished tolerance on the part of the patient. Serious adverse experiences are generally systemic in nature. The following types are those most commonly reported:
Central Nervous System
- CNS manifestations are excitatory and/or depressant and may be characterized by lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest. The excitatory manifestations may be very brief or may not occur at all, in which case the first manifestation of toxicity may be drowsiness merging into unconsciousness and respiratory arrest.
- Drowsiness following the administration of lidocaine HCl is usually an early sign of a high blood level of the drug and may occur as a consequence of rapid absorption.
- Cardiovascular manifestations are usually depressant and are characterized by bradycardia, hypotension, and cardiovascular collapse, which may lead to cardiac arrest.
- Allergic reactions are characterized by cutaneous lesions, urticaria, edema or anaphylactoid reactions. Allergic reactions may occur as a result of sensitivity either to local anesthetic agents or to the methylparaben used as a preservative in the multiple dose vials. Allergic reactions as result of sensitivity to lidocaine HCl are extremely rare and, if they occur, should be managed by conventional means. The detection of sensitivity by skin testing is of doubtful value.
- The incidences of adverse reactions associated with the use of local anesthetics may be related to the total dose of local anesthetic administered and are also dependent upon the particular drug used, the route of administration and the physical status of the patient. In a prospective review of 10,440 patients who received lidocaine HCl for spinal anesthesia, the incidences of adverse reactions were reported to be about 3 percent each for positional headaches, hypotension and backache; 2 percent for shivering; and less than 1 percent each for peripheral nerve symptoms, nausea, respiratory inadequacy and double vision. Many of these observations may be related to local anesthetic techniques, with or without a contribution from the local anesthetic.
- In the practice of caudal or lumbar epidural block, occasional unintentional penetration of the subarachnoid space by the catheter may occur. Subsequent adverse effects may depend partially on the amount of drug administered subdurally. These may include spinal block of varying magnitude (including total spinal block), hypotension secondary to spinal block, loss of bladder and bowel control, and loss of perineal sensation and sexual function. Persistent motor, sensory and/or autonomic (sphincter control) deficit of some lower spinal segments with slow recovery (several months) or incomplete recovery have been reported in rare instances when caudal or lumbar epidural block has been attempted. Backache and headache have also been noted following use of these anesthetic procedures.
- There have been reported cases of permanent injury to extraocular muscles requiring surgical repair following retrobulbar administration.
Commonly Asked Questions
Onset of action
- The amount of time taken for this medicine to show its effect is subject to variations based on the intended use and route of administration. The effect of this medicine can be observed within 45-90 seconds upon intravenous administration while the transdermal form takes 4-6 hours.
Duration of effect
- The time duration for which this medicine remains effective in the body is subject to variations based on the route of administration. The intravenous form is short acting while the other forms stay effective for longer durations.
Safe with alcohol?
- Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Is it habit forming?
- No habit forming tendencies were reported.
Usage in pregnancy?
- This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.
Usage while breast-feeding?
- This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.
This medication is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area (e.g., anal fissures, itching around the vagina/rectum). Some forms of this medication are also used to decrease discomfort or pain during certain medical procedures/exams (e.g., sigmoidoscopy, cystoscopy). Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.