Buy Capegard 500mg
capegard 500mg tablet contain the active ingredient capecitabine, which is a type of chemotherapy medicine for cancer known as a ‘cytotoxic antimetabolite’. Antimetabolites are cell-cycle specific. They attack cells at very specific phases in the cycle.
Capegard 500mg Composition
Capegard 500mg Company Name
- Cipla Ltd
Capegard 500mg How To Work
Capecitabine is a fluoropyrimidine carbamate with antineoplastic activity indicated for the treatment of metastatic breast cancer and colon cancer. It is an orally administered systemic prodrug that has little pharmacologic activity until it is converted to fluorouracil by enzymes that are expressed in higher concentrations in many tumors. Fluorouracil it then metabolized both normal and tumor cells to 5-fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP).
What Is Capegard 500mg
Capegard 500mg Tablet is a drug used for treating cancer. Capegard 500Mg Tablet is an anti-metabolite used for chemotherapy for treating patients suffering from various cancers. Capegard 500mg Tablet is used for treating breast, colon or rectal, pancreatic, gastric, ovarian, oesophageal. It comes as a pill, which is consumed after having food.
Common side effects include headache, weakness, pain¸ rashes, itching, diarrhea, fatigue, etc. It can also lead to serious side effects such as heart or kidney problems, low blood cell count and allergies. Women who are pregnant or are planning to become pregnant and breastfeeding mothers should inform their doctor before usage.
It should be avoided with antacids. People who are on health supplements or have been prescribed blood thinners should avoid its usage. People with heart or kidney issues should also refrain from taking this medicine as it can alleviate their condition.
Capegard 500mg How To Take
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Capegard 500mg Tablet is to be taken with food.
Mechanism Action Of Capegard 500mg
Capecitabine is a prodrug that is selectively tumour-activated to its cytotoxic moiety, fluorouracil, by thymidine phosphorylase, an enzyme found in higher concentrations in many tumors compared to normal tissues or plasma. Fluorouracil is further metabolized to two active metabolites, 5-fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP), within normal and tumour cells. These metabolites cause cell injury by two different mechanisms.
First, FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase (TS) to form a covalently bound ternary complex. This binding inhibits the formation of thymidylate from 2′-deaxyuridylate. Thymidylate is the necessary precursor of thymidine triphosphate, which is essential for the synthesis of DNA, therefore a deficiency of this compound can inhibit cell division.
Secondly, nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate (UTP) during the synthesis of RNA. This metabolic error can interfere with RNA processing and protein synthesis through the production of fraudulent RNA.
Capegard 500mg Instructions
Take Capegard 500mg Tablet as advised by the doctor. Do not consume larger quantities than prescribed. Do not miss any scheduled dose. Consult the doctor immediately if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Capegard 500mg Drug Interactions
- Antacids Containing Aluminum And Magnesium,
Capegard 500mg Side Effects
- Hair loss
- Blurred vision
- Dry mouth
- Muscle or joint pain
- Bone pain
- Abdominal pain
- Low white blood cell count
- Loss of appetite
Capegard 500mg Warning
Diarrhea and Dehydration – Capegard 500 mg Tablet may cause severe diarrhea which causes electrolytes loss and increases the risk of dehydration and kidney injury. Close monitoring of kidney function is necessary while receiving this medicine. If symptoms of diarrhea get worse, the treatment should be discontinued and a suitable anti-diarrheal treatment should be initiated.
Skin reactions – This medicine may cause severe skin reactions like Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis (TEN). Inform the doctor immediately if any symptoms of skin rashes and itching appear. In patients with severe skin reactions, treatment with this medicine should be discontinued and an alternative medicine should be given.
Effect on blood – Capegard 500 mg Tablet may reduce the number of white blood cells (neutrophils) and platelets. This may make the patients more prone to catch an infection. Close monitoring of blood cell count is necessary while receiving this medicine. The baseline of the blood cell count should be obtained before initiation of the treatment. Do not start the treatment if the counts are less than the normal value.
Infections – The chances of infections are more in patients receiving this medicine. Hold the treatment with this medicine and start with broad-spectrum antibiotics if there are any signs and symptoms of infection like a fever or a sore throat. Close monitoring of the body temperature and the blood cell count is necessary while receiving this medicine.
Pregnancy – This medicine is not recommended for use in pregnant women.
Breast-feeding – This medicine is not recommended for use in breastfeeding women except in life-threatening conditions. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
Capegard 500mg Precaution
Hepatic Dysfunction, Bone Marrow Suppression, Poor Nutritional Status, Warfarin Therapy. Child, Elderly, Prior Extensive Pelvic Radiation Or Alkylating Therapy. Moderate Renal Impairment; CBC With Differential; Monitor Hepatic And Renal Function. Discontinue Use If Intractable Diarrhoea, Stomatitis, Bone Marrow Suppression Or MI Develops.
Capegard 500mg Dosage
- Capegard 500mg
Capegard 500mg Uses
capegard is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. It is used to treat colorectal cancer, and breast cancer that has spread to other parts of the body.
Capegard 500mg Storage
Store Capecitabine at 20° to 25°C (68° to 77°F). Protect from light and humidity. Keep it away from children & pets.
Capegard 500mg Review
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