Buy Hepcvir 400mg
Hepcvir 400 mg manufactured by Cipla is a generic version of Sovaldi and contains the same active ingredient “Sofosbuvir”. It is a prescription medicine and should be used under proper medical guidance and advice. Do not share this medicine with others for whom it was not prescribed. Healthcare professionals prescribe specific medicine for individuals based on personal medical histories and other health factors. A medicine that works for one person may cause harm even death to someone else, even if symptoms are similar.
Hepcvir 400mg Composition
- Cipla Ltd.
Hepcvir 400mg Company Name
Hepcvir 400mg How To Work
Hepcvir 400mg Tablet is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.
What Is Hepcvir 400mg
Hepcvir 400Mg Tablet is used in combination with other medications such as ribavirin, daclatasvir and peginterferon to treat chronic hepatitis C. It functions by reducing the hepatitis C virus in the body. This helps to keep liver disorders such as cirrhosis and liver cancer at bay.
On using this medication you may experience side effects such as diarrhoea, itchiness, headache, nausea, drowsiness, rapid breathing, rapid heartbeat and skin paleness. If your reactions persist, seek the help of your health care provider right away.
Before using this medication you should tell your doctor if: you are allergic to any ingredient contained within Hepcvir 400Mg Tablet, you have any other allergies, you are taking any prescription or non-prescription drugs, you have liver/kidney disorders, you are below 18 years of age, you are pregnant or are planning to become pregnant or are nursing a baby.
Hepcvir 400mg How To Take
You should take your Hepcvir tablets 400mg swallowed whole with a glass of water once daily with or without food at the same time each day and in combination with the other antiviral drug prescribed. You should continue to take your Hepcvir tablets 400mg for as long as recommended by your doctor, which is usually 12-24 weeks, depending on HCV genotype causing the infection and the amount of liver damage.
Mechanism Action Of Hepcvir 400mg
Hepcvir tablets 400mg contain sofosbuvir, a direct-acting antiviral agent that is used in combination with other antiviral medications to treat chronic HCV infection. Sofosbuvir in Hepcvir tablets 400mg is a direct-acting nucleotide analogue inhibitor that blocks the action of the HCV NS5B polymerase, an enzyme that is essential to viral replication.
It is a nucleotide prodrug that is converted to its active form, the uridine analog triphosphate (GS-461203), which is incorporated into HCV RNA by the action of NS5B polymerase. This action of sofosbuvir in Hepcvir L tablets causes chain termination of viral RNA synthesis thereby inhibiting viral replication. Sofosbuvir in Hepcvir tablets is an effective treatment for HCV infection only when used in combination with at least one other antiviral medication.
These include interferon, which is a chemical messenger produced by host cells in response to infection by various pathogens, including viruses that stimulates the body’s own immune response, as well as directly inhibiting viral replication in infected cells. Ribavirin is a synthetic ribonucleic analogue and is incorporated into viral RNA blocking RNA synthesis; however, it does not have any antiviral activity when used alone.
The specific combination therapy regimen for HCV infection depends on the HCV genotype and the degree of liver damage due to the infection. The combination of Hepcvir tablets 400 mg and ribavirin or ribavirin with interferon lowers the amount of hepatitis C virus in the blood and may also lead to a cure of HCV infection over a number of weeks.
Hepcvir 400mg Drug Interactions
Several medications interact with Hepcvir tablets 400mg and should either not be taken while you are taking Hepcvir or only after discussion and instruction from your doctor:
- Drugs that cause a serious reaction with Hepcvir: the antiarrhythmic amiodarone can cause severe bradycardia (slow heartbeat)
- Drugs that affect Hepcvir: anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin,
- Drugs that are affected by Hepcvir: some antivirals for HIV like tenofovir,
Hepcvir 400mg Side Effects
- Ulcers or white spots in the mouth
- Lower back pain
- Decreased appetite
- Muscle pain and cramps
Hepcvir 400mg Warning
Pregnancy – This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding – This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Renal failure – This medicine should be used with caution in patients with a previous history of renal diseases due to the increased risk of renal failure. Close monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be done based on the clinical condition of the patient.
Hepatitis B – This medicine should be used with caution in patients with a known history of hepatitis B due to the increased risk of worsening of the patient’s condition. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient. It is advised to test all patients for evidence of current or prior hepatitis B before starting treatment with this medicine.
Hepcvir 400mg Precaution
You should not use Hepcvir tablets 400mg if you:
- are allergic to sofosbuvir, interferon or ribavirin or any ingredients in Hepcvir
- are allergic to interferon or ribavirin that are used in combination with Hepcvir
- are pregnant or are breastfeeding
- have kidney or liver disease other than hepatitis C
- are taking medicines that interact with Hepcvir including the antiarrhythmic amiodarone, anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, St. John’s wort, some antivirals for HIV like tenofovir
Note: Any contraindication or precautions that apply to the combination therapy regimen with ribavirin or interferon should be considered when taking Hepcvir tablets 400mg.
Hepcvir 400mg Dosage
- Hepcvir 400mg
- Hepcvir L
Hepcvir 400mg Uses
Hepcvir 400mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.
Hepcvir 400mg Storage
You should store your Hepcvir tablets 400mg below 25°C in a cool dry place.
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