Buy Hepcvir L
Hepcvir L tablets are used to treat chronic hepatitis C virus genotype 1 infection in adults. Hepatitis C is a disease of the liver caused by infection with the Hepatitis C virus (HCV) that is carried in the blood. Infection is spread by direct contact with infected blood or blood products, such as intravenous injection of drugs using unsterilised needles, tattooing or body piercing using unsterile equipment, blood transfusion or received blood products using unscreened blood, organ transplant, healthcare needle stick injury.
Infection with HCV can result in acute disease or chronic disease. Although acute symptoms may not always appear, they can appear within a few weeks or up to 6 months after infection, ranging from mild to severe, and include abdominal pain, loss of appetite, dark coloured urine, grey coloured faeces, nausea, upset stomach, fatigue. Acute HCV can result in jaundice, which causes yellowing of skin and the whites of the eyes. If the virus is not cleared from the body, which does occur spontaneously in a proportion of those infected, then they can develop symptoms of chronic HCV many years after the initial infection.
Hepcvir L Composition
Hepcvir L Company Name
- Cipla Ltd
Hepcvir L How To Work
Hepcvir L 90mg/400mg Tablet is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
What Is Hepcvir L
Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.
Chronic HCV infection causes inflammation of the liver and can lead to other more serious diseases such as liver fibrosis (early stages of liver damage and scarring) and cirrhosis (build-up of scar tissue), liver carcinoma and liver failure requiring liver transplant. Other parts of the body can be infected as the immune system produces antibodies to fight the infection and this can result in kidney failure and skin rash. HCV exists in different forms known as genotypes.
Genotype 1 is the most common type of HCV genotype and is also the most difficult to treat using other treatments. Hepcvir L tablets are effective for most genotypes but are particularly effective for genotype 1, even if the liver is damaged by cirrhosis. A cure from HCV infection is defined as no more detectable virus in the blood, which persists for at least 12 weeks after treatment. Hepcvir L tablets reduce the amount of virus in the blood and can even cure the disease, with an improved cure rate of HCV infection over other treatments.
Hepcvir L How To Take
You should continue to take your Hepcvir L tablets for as long as recommended by your doctor which is usually 12-24 weeks, depending on the amount of liver damage.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcvir L 90mg/400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Hepcvir L Drug Interactions
Drugs that cause a serious reaction with Hepcvir L: the antiarrhythmic amiodarone can cause severe bradycardia (slow heartbeat).
Drugs that affect Hepcvir L: acid reducing drugs for reflux like antacids, cimetidine and omeprazole, anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin.
Drugs that are affected by Hepcvir L: digoxin for heart failure, some antivirals for HIV like tenofovir, the statin Rosuvastatin for high cholesterol.
Hepcvir L Side Effects
- Difficulty Sleeping, And
- Low Red Blood Cell Count.
Hepcvir L Warning
You should not use Hepcvir L tablets if you:
- are allergic to ledipasvir or sofosbuvir or any ingredients in Hepcvir L
- are pregnant or are breastfeeding
- have kidney disease
- have liver disease other than hepatitis C
- are taking either ledipasvir or sofosbuvir separately
- are taking medicines that interact with Hepcvir L, including the antiarrhythmic amiodarone, acid reducing drugs for reflux like antacids, cimetidine and omeprazole, digoxin for heart failure, anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, some antivirals for HIV like tenofovir, St. John’s wort, the statin Rosuvastatin for high cholesterol
Hepcvir L Precaution
Before taking ledipasvir/sofosbuvir, tell your doctor or pharmacist if you are allergic to either of the drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease.
Hepcvir L Dosage
- Hepcvir 400mg
- Hepcvir L
Hepcvir L Uses
Hepcvir L 90mg/400mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.
Hepcvir L 90mg/400mg is a combination of ledipasvir and sofosbuvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.
Hepcvir L Storage
You should store your Hepcvir L tablets below 25°C in a cool dry place.
Hepcvir L Review
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