Janumet 50-1000mg

Buy Janumet 50-1000mg Online

Janumet is the brand name for a prescription drug that contains metformin and sitagliptin.

It’s used along with diet and exercise to lower blood sugar in people who have type 2 diabetes.

If you have type 2 diabetes, your body doesn’t make or use the hormone insulin normally, so it can’t control the amount of sugar, or glucose, in the blood.

Metformin belongs to a drug class known as biguanides.

Biguanides lower blood-sugar levels in three ways: decreasing the glucose produced by your liver; slowing absorption of sugar in the digestive system; and increasing the amount of sugar that muscle cells absorb.

How should I use this medication?

The initial dose of sitagliptin – metformin is based on the dose of each medication that is currently being taken. Your doctor will determine the dose that is appropriate for you. This medication should be taken 2 times a day with meals. The maximum dose of sitagliptin is 100 mg per day and the maximum dose of metformin is 2,000 mg per day.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to sitagliptin or metformin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (such as obstructive lung disease, severe asthma), blood problems (such as anemia, vitamin B12 deficiency), kidney disease, liver disease, disease of the pancreas (pancreatitis), stones in your gallbladder (gallstones).

Before having surgery or any X-ray/scanning procedure using iodinated contrast, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You may need to stop this medication for a short time for the surgery/procedure. Ask your doctor or dentist for instructions before your surgery/procedure.

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

Limit alcohol while using this medication because it can increase your risk of lactic acidosis and developing low blood sugar.

High fever, “water pills” (diuretics such as hydrochlorothiazide), too much sweating, diarrhea, or vomiting may cause loss of too much body water (dehydration) and increase your risk of lactic acidosis. Stop taking this medication and tell your doctor right away if you have prolonged diarrhea or vomiting. Be sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise.

When should Janumet not be used?

You should not use Janumet tablets 50/1000mg if you:

• are allergic to sitagliptin, metformin or any ingredients in Janumet
• are pregnant or are breastfeeding
• have kidney or liver disease
• have type 1 diabetes or diabetic ketoacidosis
• have symptoms of pancreatitis while taking Janumet, including severe persistent stomach pain, with or without vomiting
• have acute or chronic disease which may cause tissue hypoxia such as congestive heart failure, recent myocardial infarction, respiratory failure, pulmonary embolism, shock, acute significant blood loss, sepsis
• are over 80 without discussion with your doctor
• have a problem with alcohol
• are undergoing radiological treatment with intravascular iodinated contrast agents which may lead to renal failure, resulting in metformin accumulation and a risk of lactic acidosis
• are taking medicines that interact with Janumet, including digoxin for heart failure, thiazide diuretics and other diuretics like furosemide, calcium channel blockers like nifedipine for blood pressure and heart conditions, cimetidine for reflux and ulcers, corticosteroids such as prednisone, thyroid products, oral contraceptives, oestrogens, the anticonvulsant phenytoin, antiphsychotic phenothiazines, nicotinic acid for high cholesterol, the antibiotic isoniazid, beta blockers like propranolol for heart conditions and high blood pressure

Side Effects

• Less common
• Anxiety
• blurred vision
• chills
• cold sweats
• confusion
• cool, pale skin
• depression
• dizziness
• fast heartbeat
• headache
• increased hunger
• loss of consciousness
• mental cloudiness
• nausea
• nightmares
• not thinking clearly
• seizures
• shakiness
• slurred speech
• unusual tiredness or weakness
• Bloated or feeling of fullness
• excess air or gas in the stomach or intestines
• indigestion
• lack or loss of strength
• muscle aches
• passing gas
• sore throat
• stuffy or runny nose
• vomiting

What medications interact with Janumet?

Several medications interact with Janumet tablets 50/1000mg and should either not be taken while you are taking Janumet or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Janumet: alcohol can increase the effect of metformin on lactic acid metabolism; corticosteroids such as prednisone, thyroid products, oral contraceptives oestrogens, the anticonvulsant phenytoin, antiphsychotic phenothiazines, nicotinic acid for high cholesterol, the antibiotic isoniazid, beta blockers like propranolol for heart conditions and high blood pressure may lead to loss of glycaemic control

Drugs that affect Janumet: thiazide diuretics and other diuretics like furosemide, calcium channel blockers like nifedipine for blood pressure and heart conditions, cimetidine for reflux and ulcers

Drugs that are affected by Janumet: digoxin for heart failure, diuretics like furosemide

Uses

This combination medication is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes.

This product contains 2 medications. Sitagliptin works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes. Metformin works by helping to restore your body’s proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.