Janumet 50-500mg

Buy Janumet 50-500mg Online

Janumet contains a combination of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.

Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.

Janumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

How does Janumet 50/500mg work?

Metformin + Sitagliptin combination is used for the treatment of type 2 diabetes. It is used in conjunction with diet and exercise for effective glycaemic control.

Metformin + Sitagliptin combination may also be prescribed for other conditions as determined by the doctor.

In Metformin + Sitagliptin combination, Metformin belongs to the class of drugs called anti-diabetic drugs.  This drug acts by inhibiting hepatic glucose production, which reduces blood sugar levels.

Sitagliptin belongs to the class of drugs called anti-diabetic drugs. This drug acts by regulating the levels of glucose produced by the body after consuming food.

When should Janumet not be used?

You should not use Janumet tablets 50/500mg if you:

• are allergic to sitagliptin, metformin or any ingredients in Janumet
• are pregnant or are breastfeeding
• have kidney or liver disease
• have type 1 diabetes or diabetic ketoacidosis
• have symptoms of pancreatitis while taking Janumet, including severe persistent stomach pain, with or without vomiting
• have acute or chronic disease which may cause tissue hypoxia such as congestive heart failure, recent myocardial infarction, respiratory failure, pulmonary embolism, shock, acute significant blood loss, sepsis
• are over 80 without discussion with your doctor
• have a problem with alcohol
• are undergoing radiological treatment with intravascular iodinated contrast agents which may lead to renal failure, resulting in metformin accumulation and a risk of lactic acidosis
• are taking medicines that interact with Janumet, including digoxin for heart failure, thiazide diuretics and other diuretics like furosemide, calcium channel blockers like nifedipine for blood pressure and heart conditions, cimetidine for reflux and ulcers, corticosteroids such as prednisone, thyroid products, oral contraceptives, oestrogens, the anticonvulsant phenytoin, antiphsychotic phenothiazines, nicotinic acid for high cholesterol, the antibiotic isoniazid, beta blockers like propranolol for heart conditions and high blood pressure

Warnings

The FDA requires a black-box warning for Janumet, because it may cause a rare but serious condition called lactic acidosis (a buildup of lactic acid in the blood).

Stop taking the drug and call your doctor immediately or get emergency help if you experience any of the following side effects:

• Extreme weakness, fatigue, or discomfort
• Nausea, vomiting, or stomach pain
• Decreased appetite
• Deep and rapid breathing or shortness of breath
• Dizziness or lightheadedness
• Fast or slow heartbeat
• Flushing of the skin
• Muscle pain or weakness
• Feeling cold or blue skin

Your risk of lactic acidosis may be higher if you drink alcohol; have liver or kidney disease; are older in age; have a severe infection; or are dehydrated.

Before having surgery, including a dental procedure, tell your doctor or dentist that you are taking Janumet.

What medications interact with Janumet?

Several medications interact with Janumet tablets 50/500mg and should either not be taken while you are taking Janumet or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with Janumet: alcohol can increase the effect of metformin on lactic acid metabolism; corticosteroids such as prednisone, thyroid products, oral contraceptives oestrogens, the anticonvulsant phenytoin, antiphsychotic phenothiazines, nicotinic acid for high cholesterol, the antibiotic isoniazid, beta blockers like propranolol for heart conditions and high blood pressure may lead to loss of glycaemic control
• Drugs that affect Janumet: thiazide diuretics and other diuretics like furosemide, calcium channel blockers like nifedipine for blood pressure and heart conditions, cimetidine for reflux and ulcers
• Drugs that are affected by Janumet: digoxin for heart failure, diuretics like furosemide

Uses

Janumet 50 mg/500 mg Tablet is used in the treatment of type 2 diabetes.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Janumet 50 mg/500 mg Tablet is to be taken with food.

Janumet 50 mg/500 mg Tablet may cause stomach upset if taken on empty stomach