Ledifos Tablet
Buy Ledifos Tablet
Ledifos is the Combination of Sofosbuvir and Ledipasvir. It is really specified for Effective treatment of the Chronic (hepatitis C infection) genotype 6, 5, 4 infection. It is huge to realize that this prescription is the settled measurements mix tablet including Sofosbuvir and Ledipasvir for better oral organization. Buy Ledifos online medicine is available in the package of twenty-eight tablet In this Packets , each tablet will comprise of Sofosbuvir 400mg/Ledipasvir 90mg as the active ingredients. Patients need to swallow each tablet with the required measure of water.
Ledifos Composition
- Ledipasvir
- Sofosbuvir
Ledifos Company Name
- Hetero Drugs Ltd
Ledifos How To Work
Sofosbuvir inhibits the enzyme that the HCV uses to multiply; thus, stopping its growth. Sofosbuvir Inhibits The RNA Polymerase That The Hepatitis C Virus Uses To Replicate Its RNA.Ledipasvir Inhibits An Important Viral Phosphoprotein, NS5A, Which Is Involved In Viral Replication, Assembly, And Secretion.
What Is Ledifos
Ledifos 90Mg/400Mg Tablet helps in the treatment of chronic hepatitis C (HCV). This drug is used in a combination with another drug, to prevent the spread of HCV throughout the body.
Patients who have liver issues, or kidney problems and are undergoing dialysis, are not advised the use of Ledifos 90Mg/400Mg Tablet. Also inform your doctor about any other health issues you are suffering from and if you are taking any medicines to treat them.
Ledifos 90Mg/400Mg Tablet is meant to be taken orally, either with food or without. Antacids containing magnesium or aluminum should not be consumed for a few hours after taking the drug. The drug should be taken regularly, preferably at a particular time each day. Try not to miss any doses.
Ledifos How To Take
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ledifos 90mg/400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Mechanism Action Of Ledifos
Ledifos Drug Interactions
When Used In Combination With Peginterferon Alfa/Ribavirin Or Ribavirin Alone, All Contraindications To Peginterferon Alfa And/Or Ribavirin Also Apply To Ledipasvir/Sofosbuvir Combination Therapy.
Most Drug-Drug Interactions With Ledipasvir/Sofosbuvir Involve Pgp-Inducers Rifampicin. Concomitant Use Will Decrease The Blood Concentration Of Ledipasvir/Sofosbuvir And Thus, Have Reduced Therapeutic Effects.
Ledifos Side Effects
- Tiredness
- Headache
- Nausea,
- Difficulty Sleeping, And
- Low Red Blood Cell Count.
Ledifos Warning
Do not take Ledifos tablets if you are allergic to ledipasvir or sofosbuvir.
Do not take Ledifos tablets if you are already taking another medicine which contains sofosbuvir.
Taking Ledifos tablets in certain scenarios can involve some risk to you, or can prevent if from working as intended. Before beginning treatment, you should tell your doctor if:
- you are pregnant, planning to become pregnant, or are breast-feeding
- you are currently taking any prescription medicines, or non-prescription medicines (including herbal treatments and dietary supplements)
- you have had allergic reactions to medicines, foods, or other substances in the past
- you have kidney or liver problems
Some medicines can prevent Ledifos from working properly, or can have there own actions inhibited by Ledifos.
Simeprevir can increase the risk of ledipasvir and sofosbuvir`s side effects
Carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, St. John`s wort, or tipranavir can decrease the effectiveness of ledipasvir and sofosbuvir
The risk side effects of Digoxin or Rosuvastatin may be increased by the use of ledipasvir and sofosbuvir.
Ledifos Precaution
Bradycardia With Amiodarone Coadministration: Serious Symptomatic Bradycardia May Occur In Patients Taking Amiodarone And Sofosbuvir In Combination With Another Direct Acting Antiviral (DAA), Particularly In Patients Also Receiving Beta Blockers, Or Those With Underlying Cardiac Comorbidities And/Or Advanced Liver Disease. Coadministration Of Amiodarone With Sofosbuvir In Combination With Another DAA Is Not Recommended.
In Patients Without Alternative, Viable Treatment Options, Cardiac Monitoring Is Recommended. Pregnancy: Ribavirin May Cause Birth Defects And Fetal Death And Animal Studies Have Shown Interferons Have Abortifacient Effects; Avoid Pregnancy In Female Patients And Female Partners Of Male Patients.
Patients Must Have A Negative Pregnancy Test Prior To Initiating Therapy, Use At Least 2 Effective Methods Of Contraception And Have Monthly Pregnancy Tests.
Ledifos Dosage
- Ledifos 90Mg/400Mg
Ledifos Uses
Ledipasvir and sofosbuvir is used for treating chronic hepatitis C virus (HCV) infection in certain patients. Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body. Ledipasvir-sofosbuvir is a preferred regimen for initial treatment and retreatment of patients with genotypes 1, 4, 5, or 6 chronic hepatitis C infection.
Ledifos Storage
Store at room temperature below 30° C
- Dispense only in original container
- Do not use if seal over bottle opening is broken or missing
Ledifos Review
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