Natdac 60mg

Buy Natdac 60mg

Daclatasvir was discovered as a first-in-class inhibitor of the non-structural viral protein 5A (NS5A), a phosphoprotein that plays an important role in hepatitis C replication. The exact mechanism by which daclatasvir inhibits the NS5A replication complex is unclear, but it is believed that daclatasvir inhibits viral RNA replication and virion assembly.

Natdac 60mg Composition

• Daclatasvir

Natdac 60mg Company Name

• Natco Pharma Limited

Natdac 60mg How To Work

Natdac 60mg Tablet is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.

What Is Natdac 60mg

Natdac 60Mg Tablet is used in combination with other medications such as sofosbuvir, interferon and ribavirin for the treatment of hepatitis C infection.

On using this medication you may experience side effects such as nausea, headache, weakness, fatigue, breakdown of the red cell, diarrhoea, drowsiness, dizziness and skin rash. If your reactions persist or become worse over time seek the help of your health care provider right away.

Before using this medication you should tell your doctor if: you are allergic to any of the ingredient contained within Natdac 60Mg Tablet, you have allergy towards any food/medicine/substance, you are taking any prescription or non-prescription drugs, herbal products or dietary supplements, you have hepatitis B/ liver/heart/ disorders, you suffer from seizures, St. John’s wort, you recently had a liver transplant, you are pregnant or are planning to become pregnant or are nursing a baby.

Natdac 60mg How To Take

Natdac 60mg Tablet is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.

Mechanism Action Of Natdac 60mg

Natdac tablets 60mg contain daclatasvir, a direct-acting antiviral agent that is used to treat chronic HCV infection, in combination with sofosbuvir another antiviral medication1.  Daclatasvir in Natdac 60 inhibits the viral specific NS5A protein, which has no enzymatic activity but is essential for HCV RNA replication and post-replication assembly of the virus particle (virion).

It is highly effective at very low doses.  Sofosbuvir that is used in combination with Natdac 60 targets a different stage in the viral replication cycle.  It is a direct-acting nucleotide analogue inhibitor that blocks the action of the HCV NS5B polymerase, an enzyme that is essential to viral replication, by being incorporated into HCV RNA by the action of NS5B polymerase, which causes chain termination of viral RNA synthesis thereby inhibiting viral replication.

Daclatasvir in Natdac 60 works together with sofosbuvir to lower the amount of hepatitis C virus in the blood and may also lead to a cure of HCV infection over a number of weeks.  Ribavirin is a synthetic ribonucleic analogue and is incorporated into viral RNA blocking RNA synthesis; however, it does not have any antiviral activity when used alone.  This antiviral drug is used in triple combination therapy with daclatasvir in Natdac 60 and sofosbuvir in those with liver cirrhosis.

Natdac 60mg Drug Interactions

Drugs that cause a serious reaction with Natdac 60: the antiarrhythmic amiodarone can cause severe bradycardia (slow heartbeat).

Drugs that affect Natdac 60: anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, some antivirals for HIV like atazanavir.

Drugs that are affected by Natdac 60: digoxin for heart failure.

Natdac 60mg Side Effects

• headache,
• skin rash,
• nausea,
• fatigue and
• joint pain.

Natdac 60mg Warning

Natdac 60mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Do not drive unless you are feeling well. Some patients have reported dizziness, difficulty in concentrating, and vision problems while taking Natdac 60mg Tablet which may affect your ability to drive.

Natdac 60mg Precaution

You should not use Natdac 60 if you:

• are allergic to daclatasvir or any ingredients in Natdac 60
• are allergic to sofosbuvir that is used in combination with Natdac
• are pregnant or are breastfeeding
• have kidney or liver disease other than hepatitis C
• have been infected with hepatitis B virus as treatment for HCV can increase replication of HBV and this should be monitored
• are taking medicines that interact with Natdac 60, including the antiarrhythmic amiodarone, anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, digoxin for heart failure, some antivirals for HIV like atazanavir, St. John’s wort, rosuvastatin for high cholesterol

Natdac 60mg Dosage

• Natdac 30mg
• Natdac 60mg

Natdac 60mg Uses

Daclatasvir is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body. Daclatasvir is used to treat genotype 3 chronic hepatitis C in adults without cirrhosis. This medicine is given together with another drug called sofosbuvir.

Daclatasvir must be given in combination with sofosbuvir and it should not be used alone.

Natdac 60mg Storage

Store at 25°C (77°F); excursions permitted between 15°C and 30°C (59°F and 86°F).

Natdac 60mg Review

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