Tasigna 150mg
Buy Tasigna 150mg
Nilotinib is a medicine which is given to treat leukaemia. Leukaemia is cancer of cells in the bone marrow – these are the cells which develop into blood cells. Nilotinib is given for the type of leukaemia called chronic myeloid leukaemia (CML).
In cancer, certain cells in the body grow and multiply in a way that is ‘out of control’. Chemotherapy (anti-cancer) medicines work by inhibiting the way cells grow and increase in number. Nilotinib belongs to a group of anti-cancer medicines known as tyrosine kinase inhibitors. These medicines work by blocking the chemical messengers (called tyrosine kinases) which send signals to cells to grow. This stops the production of cancer cells.
Tasigna 150mg Composition
- Nilotinib
Tasigna 150mg Company Name
- Novartis India Ltd
Tasigna 150mg How To Work
Tasigna 150mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
What Is Tasigna 150mg
Tasigna is used to treat chronic myeloid leukaemia (CML).
CML is a type of leukaemia in which an abnormal chromosome produces an enzyme that leads to uncontrolled growth of white blood cells. Tasigna kills the abnormal cells while leaving normal cells alone.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another purpose.
Tasigna is only available with a doctor’s prescription. It is not addictive.
There is not enough information to recommend the use of this medicine in children and adolescents under 18 years of age.
Tasigna 150mg How To Take
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tasigna 150 mg Capsule is to be taken empty stomach.
Tasigna 150mg Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Some products that may interact with this drug include: antacids, H2 blockers (such as cimetidine/famotidine), proton pump inhibitors (such as omeprazole).
Other medications can affect the removal of nilotinib from your body, which may affect how nilotinib works. Examples include azole antifungals (such as itraconazole, ketoconazole), HIV protease inhibitors (such as ritonavir), macrolide antibiotics (such as clarithromycin), rifamycins (such as rifabutin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Tasigna 150mg Side Effects
- Headache,
- Nausea,
- Abdominal pain,
- Rash,
- Itching,
- Hair loss,
- Muscle pain,
Tasigna 150mg Warning
Myelosuppression: Monitor CBC during therapy and manage by treatment interruption or dose-reduction.
Cardiac and Arterial Vascular Occlusive Events: Evaluate cardiovascular status, monitor and manage cardiovascular risk factors during Tasigna therapy.
Pancreatitis and elevated serum lipase: Monitor serum lipase; if elevations are accompanied by abdominal symptoms, interrupt doses and consider appropriate diagnostics to exclude pancreatitis.
Hepatotoxicity: Monitor hepatic function tests monthly or as clinically indicated.
Electrolyte abnormalities: Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hypocalcemia, and hyponatremia. Correct electrolyte abnormalities prior to initiating Tasigna and monitor periodically during therapy.
Tumor lysis syndrome: Maintain adequate hydration and correct uric acid levels prior to initiating therapy with Tasigna.
Hemorrhage: Hemorrhage from any site may occur. Advise patients to report signs and symptoms of bleeding and medically manage as needed.
Fluid retention: Monitor patients for unexpected rapid weight gain, swelling, and shortness of breath. Manage medically.
Effects on Growth and Development in Pediatric Patients: Monitor growth and development in pediatric patients.
Embryo-Fetal toxicity: Advise patients of potential risk to a fetus and to use effective contraception.
Treatment Discontinuation: Patients must have typical BCR-ABLÂ transcripts. An FDA-authorized test with a detection limit below MR4.5 must be used to determine eligibility for discontinuation. Patients must be frequently monitored by the FDA authorized test to detect possible loss of remission.
Tasigna 150mg Precaution
Tasigna 150mg Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Tasigna 150mg Capsule may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Tasigna 150mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Tasigna 150 mg Capsule may be needed. Please consult your doctor.
Tasigna 150mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tasigna 150 mg Capsule may not be needed in these patients. Please consult your doctor.
Tasigna 150mg Dosage
- Tasigna 150mg
- Tasigna 200mg
Tasigna 150mg Uses
Tasigna 150mg Capsule is used in the treatment of blood cancer (Chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
Tasigna 150mg Storage
Keep your medicine in the original container until it is time to take it.
Store it in a cool dry place.
Do not store Tasigna or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills.
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