Temonat 100mg

Buy Temonat 100mg

Temozolomide is an oral alkylating agent which can be used for the treatment of Grade IV astrocytoma — an aggressive brain tumor, also known as glioblastoma multiforme. The agent was developed by Malcolm Stevens and his team at Aston University in Birmingham, A derivative of imidazotetrazine, temozolomide is the prodrug of MTIC (3-methyl-(triazen-1-yl)imidazole-4-carboxamide).

Temonat 100mg Composition

• Temozolomide

Temonat 100mg Company Name

• Natco Pharma Ltd.

Temonat 100mg How To Work

Temonat 100mg Capsule is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

What Is Temonat 100mg

Temozolomide interferes with the development of cancer cells, slowing their growth and spread in the body. Temozolomide is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.  This medication is classified as an “alkylating agent.”

Temozolomide is an antitumour agent. Temozolomide is used for the treatment of patients with specific forms of brain tumours: newly-diagnosed glioblastoma multiforme. Temozolomide is first used together with radiotherapy (concomitant phase of treatment) and after that alone (monotherapy phase of treatment). malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma. Temozolomide is used in these tumours if they return or get worse after standard treatment.

Temonat 100mg How To Take

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Temonat 100 mg Capsule is to be taken empty stomach.

Temonat 100mg Side Effects

• Rash,
• Headache,
• Dizziness,
• Convulsion,
• Coordination disorder,
• Insomnia (difficulty in sleeping),
• Vomiting,
• Weakness,
• Nausea,
• Loss of appetite,
• Hair loss,
• Fatigue,
• Fever,
• Diarrhoea,
• Memory loss,
• Constipation,
• Hemiparesis (weakness on one side of the body),
• Viral infection.

Temonat 100mg Warning

Temonat 100mg Capsule is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

Temonat 100mg Capsule is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.

Temonat 100mg Capsule may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Interaction with alcohol is unknown. Please consult your doctor.

Temonat 100mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Temonat 100 mg Capsule may not be needed in these patients. Please consult your doctor. Cautious use is advised in patients with severe kidney disease while they are taking Temonat 100 mg Capsule.

Temonat 100mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Temonat 100mg Capsule may be needed. Please consult your doctor.

Limited information is available on the use of Temonat 100mg Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Temonat 100mg Precaution

Swallow full tablets on an empty stomach, one hour before your meal.

Avoid being near people who are sick or have infections. Consult your doctor if you develop symptoms of opportunistic infections (such as Pneumocystis jirovecii pneumonia) and reactivation of infections (such as hepatitis B virus) Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Be aware about your specific risk.

You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.

Your blood will be tested frequently during treatment to monitor the side effects of temozolomide on your blood cells as you may have a small risk of other changes in blood cells, including leukemia.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Do not drink alcohol while taking temozolomide.

Do not drive or operate machinery while using temozolomide as it may make you tired or sleepy.

Both male and female patients should take effective contraceptive precautions during and after 6 months of treatment. Male patients should seek advice on conservation of sperm prior to treatment as temozolomide treatment may cause infertility.

Temonat 100mg Dosage

• Temonat 20mg
• Temonat 100mg
• Temonat 250mg

Temonat 100mg Uses

Temozolomide is used for the treatment of anaplastic astrocytoma, glioblastoma multiforme (GBM) (types of brain tumors). Temozolomide is classified as an alkylating agent. Alkylating agents are most active in the resting phase of the cell.  These drugs are cell-cycle non-specific. Temozolomide is similar to the drug dacarbazine.  It acts as a “pro-drug” meaning it needs to be transformed to its active (cancer fighting) form by the body’s metabolism.

Temonat 100mg Storage

Keep out of the reach and sight of children, preferably in a locked cupboard. Accidental ingestion can be lethal for children. Do not use Temozolomide after the expiry date which is stated on the label and carton. The expiry date refers to the last day of the month. Bottle presentation Do not store above 30°C. Store in the original bottle in order to protect from moisture. Keep the bottle tightly closed.Sachet presentation Do not store above 30°C Tell your pharmacist if you notice any change in the appearance of the capsules. Medicines should not be disposed of via wastewater of household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Temonat 100mg Review

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