Buy Zudena 100mg
Zudena 100 mg contains the active ingredient Udenafil – the latest PDE5 inhibitor (phosphodiesterase type 5 inhibitor) type of medication for erectile dysfunction (ED) treatment. Zudena (Udenafil) is the new approved ED drug.
Zudena 100mg Composition
- Udenafil 100 mg
Zudena 100mg Company Name
- Sunrise Remedies Pvt Ltd.
Zudena 100mg How To Work
Udenafil is a drug used in urology to treat erectile dysfunction. It belongs to a class of drugs called PDE5 inhibitor, which many other erectile dysfunction drugs such as avanafil, sildenafil, tadalafil, and vardenafil also belong to.
What Is Zudena 100mg
Zudena is efficacious in once daily dosing for erectile dysfunction. Udenafil the active substance of Zudena pills is the latest ED treatment drug developed in South Korea and available on the market as Zudena 100 mg pills (by Sunrise Remedies) or Zydena 100 mg pills.
Zudena 100mg How To Take
Zudena is taken orally, regardless of the meal. Do not break or split a Zudena tablet. Swallow it whole.
Mechanism Action Of Zudena 100mg
Zudena Udenafil 100mg inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by udenafil enhances erectile function by increasing the amount of cGMP.
Zudena 100mg Instructions
Do not use Udenafil in combination with other treatments for erectile dysfunction.
Do not take Udenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (“poppers”). Taking Udenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Zudena 100mg Drug Interactions
Inhibitors of cytochrome P450 isoenzyme CYP3A4 (ketoconazole, itraconazole, ritonavir, indinavir, cimetidine, erythromycin, grapefruit juice) may enhance the action of Udenafil.
Ketoconazole (400 mg) increases the bioavailability and Cmax of Udenafil (100 mg) almost 2-fold (212%) and 0.8-fold (85%), respectively.
Ritonavir and indinavir substantially increases the effects of Udenafil.
Dexamethasone, rifampin, and anticonvulsants drugs (carbamazepine, phenytoin and phenobarbital) may accelerate the metabolism of Udenafil, so joint application with the above medications weakens the effect of Udenafil.
The joint application of Udenafil (30 mg / kg orally) and nitroglycerin (2.5 mg / kg once, w / w) did not reveal any effect on the pharmacokinetics of Udenafil in experimental studies, but the simultaneous use of nitroglycerin and of Udenafil is not recommended because of possible reduce blood pressure.
Udenafil and drugs from the group of alpha-blockers are vasodilator, therefore, in the joint admission should be appointed at the minimum doses.
Zudena 100mg Side Effects
- dry mouth,
- abdominal discomfort
- difficulty sleeping.
Zudena 100mg Warning And Precaution
Sexual activity is a potential risk for patients with cardiovascular disease, so treatment of erectile dysfunction, including using of Udenafil, should not hold for men with heart disease, in which sexual activity is not recommended.
Patients with obstruction of blood outflow from the left ventricle (aortic stenosis) may be more sensitive to the action of vasodilators, including inhibitors of PDE. Despite the lack of clinical trials of cases of prolonged erection (longer than 4 hours) and priapism (painful erections lasting more than 6 h), such phenomena are peculiar to this class of drugs. In the event of an erection lasting more than 4 hours (regardless of pain), patients should immediately seek medical help. In the absence of timely treatment of priapism can lead to irreversible damage to the erectile tissue and erectile function.
List of those who must take Zudena with extra caution:
Patients with uncontrolled hypertension,
Patients with hereditary degenerative diseases of the retina (including retinitis pigmentosa, proliferative diabetic retinopathy);
Patients who have undergone over the last 6 months of stroke, myocardial infarction or coronary artery bypass grafting;
Patients with severe hepatic or renal impairment; presence of congenital long QT syndrome, or an increase in the QT interval as a result of taking the drugs; predisposition to priapism;
Patients with anatomical deformation of the penis; the presence of penile implant; sexual activity in patients with diseases of the cardiovascular system such as unstable angina or angina occurring during sexual intercourse, chronic heart failure (II-IV functional class NYHA classification), which developed during the last 6 months, uncontrolled heart rhythm disordershypotension;
Zudena 100mg Dosage
The Recommended dose is 100 mg, taken 30 minutes before anticipated sexual activity
Zudena 100mg Safety Information
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Zudena 100mg Uses
Treatment of erection disorders, characterized by the inability to achieve or maintain penile erection sufficient for satisfactory sexual intercourse.
Zudena has the following active ingredient: Udenafil. Zudena (Udenafil) is a therapeutic agent hypothesized to improve erectile dysfunction through interaction with the phosphodiesterase type 5 (PDE5) enzyme.
Zudena 100mg Storage
Store Zudena in a dry, dark place at a temperature no higher than 86° F (30° C). Do not store drugs in the bathroom. Keep all drugs out of the reach children and pets.
Zudena 100mg Review
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